Implication of halogen bonding in ligand substitution reactions: solid-state studies
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چکیده
منابع مشابه
Halogen Interactions in Protein-Ligand Complexes: Implications of Halogen Bonding for Rational Drug Design
Halogen bonding interactions between halogenated ligands and proteins were examined using the crystal structures deposited to date in the PDB. The data was analyzed as a function of halogen bonding to main chain Lewis bases, viz. oxygen of backbone carbonyl and backbone amide nitrogen. This analysis also examined halogen bonding to side-chain Lewis bases (O, N, and S) and to the electron-rich a...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances
سال: 2015
ISSN: 2053-2733
DOI: 10.1107/s205327331509823x